Primary

• Orochimaru Former teammate of Tsunade
• Orochimaru Former Disciple of Hiruzen Sarutobi
• Orochimaru Former teammate of Jiraiya
• Orochimaru Father of Mitsuki
• Orochimaru "favorite" former hokage Tobirama Senju
• Orochimaru one of his "little lab rats" Yamato
• Orochimaru survival fight against Hanzo of the Salamander
• Orochimaru Genetic Template of Mitsuki

Extended

• Hiruzen Sarutobi Grandfather of Konohamaru Sarutobi
• Hiruzen Sarutobi Former Teacher of Orochimaru
• Hiruzen Sarutobi Former Teacher of Jiraiya (young)
• Hiruzen Sarutobi Father of Asuma Sarutobi
• Hiruzen Sarutobi former student of Tobirama Senju
• Hiruzen Sarutobi Former teammate of Homura Mitokado
• Hiruzen Sarutobi Former teammate of Koharu Utatane
• Jiraiya In love with Tsunade
• Jiraiya Former Disciple of Hiruzen Sarutobi
• Jiraiya Mentor of Naruto Uzumaki
• Jiraiya Friend of Minato Namikaze
• Jiraiya former teacher of Nagato Uzumaki
• Jiraiya former teacher of Yahiko
• Jiraiya former teacher of Konan
• Jiraiya Former teammate of Orochimaru
• Jiraiya survival fight against Hanzo of the Salamander
• Tsunade Granddaughter of Hashirama Senju
• Tsunade Lover of Dan Katou
• Tsunade Granddaughter of Mito Uzumaki
• Tsunade Grandniece of Tobirama Senju
• Tsunade survival fight against Hanzo of the Salamander
• Tsunade Former teammate of Jiraiya
• Tsunade Former teammate of Orochimaru
• Tsunade Teacher of Sakura Haruno
• Tsunade Student of Hiruzen Sarutobi
• Tsunade Older Sister of Nawaki
• Tobirama Senju Younger Brother of Hashirama Senju
• Tobirama Senju Uncle of Tsunade
• Tobirama Senju former teacher of Hiruzen Sarutobi
• Tobirama Senju former teacher of Homura Mitokado
• Tobirama Senju former teacher of Koharu Utatane
• Tobirama Senju really hates Orochimaru
• Tobirama Senju Co-worker of Minato Namikaze
• Tobirama Senju Enemy of Madara Uchiha
• Tobirama Senju Enemy of Izuna Uchiha
• Tobirama Senju Brother-in-law of Mito Uzumaki
• Yamato clone of Hashirama Senju
• Yamato a "lab rats"/sworn enemy Orochimaru
• Mitsuki son of Orochimaru
• Mitsuki Teammate of Sarada Uchiha
• Mitsuki Teammate of Boruto Uzumaki
• Mitsuki Clone of Orochimaru
• Hanzo of the Salamander murdered by Pain
• Hanzo of the Salamander Friend of Mifune