Primary

• Hashirama Senju Grandfather of Tsunade
• Hashirama Senju Older Brother of Tobirama Senju
• Hashirama Senju Grandfather of Nawaki
• Hashirama Senju Friend of Madara Uchiha
• Hashirama Senju Husband of Mito Uzumaki
• Hashirama Senju reincarnation of Asura Otsutsuki
• Hashirama Senju held the first meeting of the kages with Ishikawa
• Hashirama Senju held the first meeting of the kages with Byakuren
• Hashirama Senju Genetic Template of Zetsu
• Hashirama Senju Genetic Template of Yamato

Extended

• Tsunade Granddaughter of Hashirama Senju
• Tsunade Lover of Dan Katou
• Tsunade Granddaughter of Mito Uzumaki
• Tsunade Grandniece of Tobirama Senju
• Tsunade survival fight against Hanzo of the Salamander
• Tsunade Former teammate of Jiraiya
• Tsunade Former teammate of Orochimaru
• Tsunade Teacher of Sakura Haruno
• Tsunade Student of Hiruzen Sarutobi
• Tsunade Older Sister of Nawaki
• Nawaki Younger Brother of Tsunade
• Nawaki Grandson of Hashirama Senju
• Nawaki Grandson of Mito Uzumaki
• Tobirama Senju Younger Brother of Hashirama Senju
• Tobirama Senju Uncle of Tsunade
• Tobirama Senju former teacher of Hiruzen Sarutobi
• Tobirama Senju former teacher of Homura Mitokado
• Tobirama Senju former teacher of Koharu Utatane
• Tobirama Senju really hates Orochimaru
• Tobirama Senju Co-worker of Minato Namikaze
• Tobirama Senju Enemy of Madara Uchiha
• Tobirama Senju Enemy of Izuna Uchiha
• Tobirama Senju Brother-in-law of Mito Uzumaki
• Zetsu Clone of Hashirama Senju
• Yamato clone of Hashirama Senju
• Yamato a "lab rats"/sworn enemy Orochimaru
• Madara Uchiha Older Brother of Izuna Uchiha
• Madara Uchiha Friend of Hashirama Senju
• Madara Uchiha Enemy of Tobirama Senju
• Madara Uchiha reincarnation of Indra Otsutsuki
• Madara Uchiha Master of Tobi
• Mito Uzumaki Grandmother of Tsunade
• Mito Uzumaki Grandmother of Nawaki
• Mito Uzumaki Wife of Hashirama Senju
• Mito Uzumaki Sister-in-law of Tobirama Senju
• Asura Otsutsuki son of Hagoromo Otsutsuki
• Asura Otsutsuki Brother of Indra Otsutsuki
• Asura Otsutsuki Grandson of Tenji
• Asura Otsutsuki founder of the clan of Hashirama Senju
• Asura Otsutsuki Nephew of Hamura Otsutsuki
• Asura Otsutsuki grandson of Kaguya Otsutsuki
• Ishikawa grandfather of Yukito Tsujii
• Ishikawa grandfather of Onoki
• Ishikawa Grandfather of Kurotsuchi
• Ishikawa former teacher of Mu
• Byakuren predecessor of Gengetsu Hozuki (Second Mizukage)
• Byakuren was there at first kage meeting with Hashirama Senju
• Byakuren was there at first kage meeting with Reto
• Byakuren was there at first kage meeting with A (First Raikage)
• Byakuren was there at first kage meeting with Ishikawa