|The game is set in ancient China during and after the fall of the Han dynasty with some major differences, most notably; Most of the male characters in the novel have become female and The Three Kingdoms that were formed after the Han Dynasty, had already been established. Despite each kingdom being ruled by an independent monarchy, the three kingdoms are still loyal to the Han empire. However, the empire is on the verge of collapse as civil unrest, banditry and infighting bring turmoil to the nation.
As the empire finally collapse and warlords wage war with each other, amidst the turmoil several major factions are formed, ready to rule and unite the fractured nation. These major factions (5 in Koihime Musō, 7 in the sequel) are the Shoku faction (Chinese: 蜀, Shǔ) led by Kazuto Hongō in Koihime Musō and in the sequel, Queen Ryūbi (Liu Bei) of the Kingdom of Shu, the Gi faction (Chinese: 魏, Wèi) led by Queen Sōsō (Cao Cao) of the Kingdom of Wei, the Go faction (Chinese: 吳, Wú) led by Princess Sonken (Sun Quan) of the Kingdom of Wu and in the sequel, her older sister Queen Sonsaku (Sun Ce), the Tōtaku faction (Chinese: 董卓, Dong Zhuo) led by Governess Tōtaku, Governor of Dong province, the En/Yuan faction led by Lady Enshō, Lord of Yuan province, and in the sequel the Kōkintō/Yellow Turban Rebels led by the Zhang sisters, Chōkaku, Chōhō and Chōryō and the Nanban/Southern Barbarians led by Mōkaku. (The anime is set before the Han empire fell and before the power struggle between the warlords began.)