The world of Nightwalker is bathed in blood and steeped in mystery. Shido is a private Detective who takes cases that primarily deal with strange murders. These murders all have one thing in common, the Night Breed! The Breed are a distant cousin of the Vampire, whose thirst for blood and penchant for violence is unparalleled. Shido, being a vampire, is disgusted by the way the Breed act and has pledged himself to rid the world of them! Shido feeds off of his sassy partner, Yayoi, who has police contacts that keep them out of trouble. Shido's secretary, Riho, is infatuated with Shido and wants to date him. But what will happen when she learns of his dark secret? And who is the mysterious Cain? All these questions and more will be answere in Nightwalker: The Midnight Detective!